Appendix: Scientific References

MEN’S Formula 7-Beta-Hydroxy-DHEA: Lardy H, Marwah A, Marwah P.C(19)-5-ene steroids in nature. Vitam Horm. 2005;71:263-99. Review. Ergosteroids IV: Synthesis and Biological Activity of Steroid Glucuronosides, Ethers, and Alkylcarbonates. Marwah P, Marwah A, Kneer N, Lardy H. Steroids 66 (2001) 581-595 DHEA and DHEA-S: A Review. Kroboth P, Salek F, Pittenger A, Fabian T. J Clin Pharmacol 1999;39:327-348 The Importance of Being Dehydroepiandrosterone Sulfate (In The Blood of Primates). Roberts E. Biochem Pharmacol 1999;57:329-346 7-Hydroxylation of Dehydroepiandrosterone By Rat Liver Homogenate. Starka L, Kutova J. Biochem Biophys Acta 1962;56:76-82 Studies of the Enzyme Complex Responsible for Pregnelone and Dehydroepiandrosterone 7a-Hydroxylation in Mouse Tissues. Doostzadeh J, Morfi n R. Steroids 1996;61:613-620 Ergosteroids II: Biologically Active Metabolites and Synthetic Derivatives of Dehydroepiandrosterone. Lardy H, Kneer N, Wei Y, Partridge B, Marwah P. Steroids 1998;63:158-165 An Acute Oral Gavage Study of 3ß-acetoxyandrost-5-ene-7,17-dione (7-oxo-DHEA-acetate) In Rats. Lardy H, Henwood S, Weeks C. Biochem Biophys Res Commun 1999;254:120-123 An Escalating Dose Oral Gavage Study of 3ß-aceoxyandrost-5-ene-7,17-dione (7-oxo-DHEA-acetate) in Rhesus Monkeys. Henwood S, Weeks C, Lardy H. Biochem Biophys Res Commun 1999;254:124-126 Safety and Pharmacokinetic Study With Esccalating Doses of 3-acetyl-7-oxo-DHEA in Healthy Male Volunteers. Davidson M, Marwah A, Sawchuk R, Maki K, Marwah P, Weeks C, Lardy H. Clin Investigative Med 2000 Oct;23(5):300-310 20-Beta-Hydroxy-Ecdysone-2-Acetate-Ester: Uchiyama, M, and T Yoshida. 1974, Effect of ecdysterone on carbohydrate and lipid metabolism: In Burdette WJ, editor. Invertebrate Endocrinology and Hormonal Heterophylly. 401–416. Springer-Verlag, Berlin. Syrov VN, Kurmukov AG. 1976c. Anabolic activity of phytoecdysone-ecdysterone isolated from Rhaponticum Carthamoides. Farmakologiya I Toksikologiya 39: 690-693. Syrov, VN, V Saatov, ShSh Sagdullaev, and AU Mamatkhanov. 2001, Study of the structure – anabolic activity relationship for the phytoecdysteroids extracted from some plants of central Asia: Pharmaceutical Chemistry Journal. 35 667–671. Syrov, VN. 1984, Mechanism of the anabolic action of phytoecdysteroids in mammals: Biologichekie Nauki (Moscow).(11):16–20. WOMEN’S Formula Phosphatidylserine: Kingsley MI, Wadsworth D, Kilduff LP, McEneny J, Benton D. Effects of soy lecithin phosphatidic acid and phosphatidylserine complex (PAS) on the endocrine and psychological responses to mental stress. Stress. 2004 Jun;7(2):119-26. Benton D, Donohoe RT, Sillance B, Nabb S. The infl uence of phosphatidylserine supplementation on mood and heart rate when faced with an acute stressor. Nutr Neurosci. 2001;4(3):169-78. Daidzen: Wu J, Oka J, Higuchi M, Tabata I, Toda T, Fujioka M, Fuku N, Teramoto T, Okuhira T, Ueno T, Uchiyama S, Urata K, Yamada K, Ishimi Y. Cooperative effects of isofl avones and exercise on bone and lipid metabolism in postmenopausal Japanese women: a randomized placebo-controlled trial. Metabolism. 2006 Apr;55(4):423-33. Ross JA, Kasum CM. Dietary fl avonoids: bioavailability, metabolic effects, and safety. Annu Rev Nutr. 2002;22:19-34. Epub 2002 Jan 4. Review. Ohno S, Shinoda S, Toyoshima S, Nakazawa H, Makino T, Nakajin S. Effects of fl avonoid phytochemicals on cortisol production and on activities of steroidogenic enzymes in human adrenocortical H295R cells. J Steroid Biochem Mol Biol. 2002 Mar;80(3):355-63. Kandulska K, Nogowski L, Szkudelski T. Effect of some phytoestrogens on metabolism of rat adipocytes. Reprod Nutr Dev. 1999 Jul-Aug;39(4):497-501. Setchell KD, Lydeking-Olsen E. Dietary phytoestrogens and their effect on bone: evidence from in vitro and in vivo, human observational, and dietary intervention studies. Am J Clin Nutr. 2003 Sep;78(3 Suppl):593S-609S. Review.

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